Chaoshuang Lin, MD

Titles

Professor of Infection Diseases

The Third Affiliated Hospital of the Sun Yat-sen University
Associate Director of Guangdong Association of Hepatology

Secretary of Guangdong Doctor Association.

Research Interests

• Hepatitis B

• Hepatitis C

• Clinical trials

• Maternal-to-fetal transmission (MTFT)

• Clinical outcomes analyses

She has engaged in the field of infection diseases in the past 20 years. Her early work focuses on vaccination of hepatitis B. She specializes in treatment of hepatitis B & C, where she gains sufficient experiences in treating the serve hepatitis. She receives research grant from the Nature Science Fund of the Science Technology Government Agency of Guangdong Province and China. One of her research studying the prevention and cure of major infectious diseases, including AIDS and hepatitis, received grant from the “Eleven-Five” Special Technology Topic of China.

She conducted numerous clinical trials to evaluate the safety and effectiveness of new drugs for the management of patients with hepatitis. Her current study involves the topic of maternal-to-fetal transmission (MTFT) of hepatitis B virus (HBV).

Education and Experience

1988-1993 B.S. the Sun Yat-sen University
1996-1999 M.S. the Sun Yat-sen University
2005-2008 M.D. the Sun Yat-sen University 

Professional Appointment

1993-present The Third Affiliated Hospital of the Sun Yat-sen University,

1993-1998 Resident

1999-2006 Attending Phycisian

2007-2012 Associate Professor
2012-present  Professor

Publications  

1.Lin Chaoshuang, Zhao Zhixin, Wang Xiaohong, Huang Zhanlian, Gao Zhiliang. Clinical analysis of 52 cases of neurocysticercosis. Tropical Doctor. July 2008; 38:192~194.

2.Lin Chaoshuang, Chong Yutian, Yang Lin, Xie Shibin, Gao Zhiliang. The efficacy of lamivudine taken before Liver Transplantation in the prevention of HBV recurrence in patients with hepatitis B virus-related terminal liver disease. Guangdong Medicine.2007；28（10）：1617-1619。

3.LIN Chao-shuang, ZHU Jian-yun , MAI Li ,Wen-Hui LEE , GAO Zhi-liang. Status of vaccination against hepatitis B among postgraduate students in medical higher education institutions in Guangzhou. Chinese J Exp Clin Virol. 2007；21（2）：114-116.

4.Chao-Shuang Lin, Shi-Bin Xie, Jing Liu, Zhi-Xin Zhao, Yu-Tian Chong*, and Zhi-Liang Gao*. Effect of revaccination using different schemes among adults with low or undetectable anti-HBs titers after hepatitis B virus vaccination. Clinical and Vaccine Immunology. 2010;17(10):1548–1551.

5.Chaoshuang Lin, Jianyun Zhu, Yubao Zheng, Youming Chen, Zhebin Wu, Yutian Chong, Zhiliang Gao. Effect of GM-CSF in combination with hepatitis B vaccine on revaccination of healthy adult non-responders. Journal of Infection. 2010,60：264-270. J Infect (2010).

6.Chao-shuang Lin, Jian-yun Zhu, Yu-bao Zheng, Yu-tian Chong, Zhi-liang Gao. Status of HBV Infection and Vaccination among Health Care Workers in a Public Teaching Hospital. Hepatology International. 2010;P102 PP030.

7. C.S. Lin, D.C. Li, C. Ma. Investigation of HBV infection rate and virus genotypes of Yao population in Guangdong Ruyuan. International Journal of Infectious Disease. 2011, 15(Supple 1): S70.

8. C.S. Lin, L.H. She, J. Liu, Z.X. Zhao, Z.L. Gao. A five-year follow-up of ninety-nine hepatitis C patients. International Journal of Infectious Disease. 2011, 15(Supple 1): S81.

9. Chao-Shuang Lin, Jian-Guo Li, Yu-Feng Zhang, Lan-Hui She, Yu-Tian Chong, Zhi-Liang Gao. HBV Vaccination among Health Care Workers in a Comprehensive Hospital. Hepatology International. 2011;P85 PP04-02.

10. Chao-Shuang Lin, Jian-Guo Li, Yu-Feng Zhang, Yu-Tian Chong, Zhi-Liang Gao. A Preliminary Study of Expression of CD150 (SLAM) in the Non-/hypo-Responders and Responders of Hepatitis B Vaccine. Hepatology International. 2011;P72 PP03-01.

11. Chao-Shuang Lin, Qing-Xian Cai, Zhan-Lian Huang, Bing-Liang Lin, Yu-Tian Chong,Zhi-Xin Zhao*, Zhi-Liang Gao. DIETHYLENE GLYCOL POISONING AND LIVER FUNCTION FOLLOWING ACCIDENTAL DIETHYLENE GLYCOL INJECTION. EXCLI Journal. 2012;11:98-107.  ISSN 1611-2156

12. Chao-Shuang Lin, Lan-Hui She, Xiao-Hong Zhang, Zhi-Xin Zhao, Zhi-Liang Gao. Decrease of Myeloid-derived suppressor cells in the peripheral blood of patients with chronic hepatitis C after 4 weeks of antiviral treatment. Hepatology International. 2012; P5 PS 01-04.

13．Jing Liu*, Chao-Shuang Lin*, Wei-Qiang Gan, Yu-Bao Zheng, Zhe-Bin Wu, Zhi-Xin Zhao，Zhi-Liang Gao. Effect of healthcare insurance policy on the quality of life of chronic hepatitis C patients receiving interferon α-2a plus ribavirin therapy. Experimental and Therapeutic Medicine. 2012；3: 1062-1066.

14. Li-Rong Lu, Xiang-Yang Wang, De-Chang Li, Zhan-Lian Huang, Jing Liu, Chao-Shuang Lin*. A preliminary study of CD150 expression in responders and non-responders to the Hepatitis B vaccine. Biomedical Research 2014;25(2):149-152.

15．Ying Liu*, Lan-Hui She*, Xiang-Yang Wang, Geng-Lin Zhang, Ying Yan,Chao-ShuangLin, Zhi-Xin Zhao, Zhi-Liang Gao. Expansion of myeloid-derived suppressor cells from peripheral blood decreases after 4-week antiviral treatment in patients with chronic hepatitis C. Int J Clin Exp Med 2014;7(4):998-1004.

16．Li-Rong Lu, Jing Liu, Zhen Xu, Geng-Lin Zhang, De-Chang Li, Chao-Shuang Lin*. Expression and Clinical Significance of Myeloid Derived Suppressor Cells in Chronic Hepatitis B Patients. Asian Pac J Cancer Prev,2014；15 (10), 4367-4372. 

17．Gang Ning, Lanhui She, Lirong Lu, Ying Liu, Yingfu Zeng,Ying Yan, and Chaoshuang Lin. Analysis of Monocytic and Granulocytic Myeloid-Derived Suppressor Cells Subsets in Patients with Hepatitis C Virus Infection and Their Clinical Significance. BioMed Research International.2015, Article ID 385378, 8 pages.

18．Yu-Bao Zheng, Yu-Rong Gu, Min Zhang, Ke Wang, Zhan-lian Huang, Chao-Shuang Lin* and Zhi-Liang Gao* Health care workers in Pearl River Delta Area of China are not vaccinated adequately against hepatitis B: a retrospective cohort study. BMC Infectious Diseases.2015;15:542.

19．Qiyi Zhao, Pei-pei Wang, Zhan-lian Huang, Liang Peng, Chaoshuang Lin*, Zhiliang Gao*, Shicheng Su. Tumoral indoleamine 2, 3-dioxygenase 1 is regulated by monocytes and T lymphocytes collaboration in hepatocellular carcinoma. Oncotarget,1-10. Advance Publications 2016.

 Contact

Department of Infectious Diseases

The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

Tel phone: (0086020) 85252029
Fax: (0086020) 85252559
E-mail: linchaoshuang@126.com