Jian Zhang, MD, PhD
Titles
Professor of Surgery
Department of Hepatobiliry Surgery and Liver Transplantation of the Third Affiliated Hospital of Sun Yat-Sen University
Research Interests
Organ transplantation
Liver surgery
His early work focused on hepatobiliary surgery. He has since been involved in the field of organ transplantation for the past 10 years. He had participated in 500s liver transplantation. Be skillful with operation of liver transplantation. Have some experience in postoperative management in liver transplantation, which includes diagnosis and treatment of hepatic vascular and billiary duct complication, monitoring of postoperative immuno-rejection and guidance of immunosuppressive drug.
Education and Experience
MD, Guiyang Medical collage (1996)
PhD, Sichuan University (2003)
Post-doctor Fellow, Sun Yat-Sen University (2003-2005)
Residency, The Affiliated Hospital of Guiyang Medical collage
Visiting surgeon, The Affiliated Hospital of Guiyang Medical collage
Fellowship, Third Affiliated Hospital of Sun Yat-Sen University
Publications
1.Jian Zhang, Ning Na, Nan Jiang, Guo-Ying Wang, Hua Li.Effects of C5a receptor on angiogenesis and tumor progression in hunman hepatocellular carcinoma implantation mice. Hepatology, 2011, 54(4):1299A.
2.Zhang Jian, LI Hua, Wang Gen-shu, Jiang Nan, Yang Yang and Chen Gui-hua. Effects of rapamycin on angiogenesis and tumor progression in human hepatocellular carcinoma implantation mice. Chin Med Abstracts (Surgery), 2009, 18(4): 247.
3.J. Zhang, H. Li, N. Jiang, Q. Zhang, G.-S. Wang, H.-M. Yi, B.-S. Fu, G.-Y. Wang, Y. Yang, and G.-H. Chen. Effects of gene transfer CTLA4Ig and anti-CD40L monoclonal antibody on islet xenografts rejection in mice. Transplant Proc, 2010, 42(5): 1835–1837.
4.Zhang Jian, Li Hua, Jiang Nan, Wang Guo-ying, Fu Bin-sheng, Wang Gen-shu, Yang Yang, Chen Gui-hua. Inhibition of rejection in murine islet xenografts by CTLA4Ig and CD40LIg gene transfer. Chin Med J 2010, 123(21):3106-3109.
5.Jian Zhang, Nan Jiang, Huanbing Zhu, Dongliang Yin, Yingcai Zhang. Inhibition of on angiogenesis and tumor growth in human hepatocellular carcinoma implantation mice by silencing CXCR7. Hepatology, 2012, 56(S1): 612A.
6.LI Hua, JIANG Nan, ZHANG Jian, WANG Gen-shu, YANG Yang and CHEN Gui-hua. Transplantation of human thioredoxin gene-modified hepatocytes for treatment of acute liver failure in rat model. Chin Med J, 2009, 122(21): 2631-2635.
7.Jiang N, Li H, Wang GS, Zhang J, Zhang JF, Yi SH, Yang Y, Cai CJ, Lu MQ, Chen GH. Acute leukemia, a rare but fatal complication after liver transplantation acute leukemia, a rare but fatal complication after liver transplantation. Leuk Res. 2009; 33(10):1349-51.
8.Qi Zhang, Yang Yang, Jian Zhang, Guo-Ying Wang, Wei Liu, Dong-Bo Qiu, Zi-Qing Hei, Qi-Long Ying, Gui-Hua Chen. Efficient derivation of functional hepatocytes from mouse induced pluripotent stem cells by a combination of cytokines and sodium butyrate. Chin Med J (Engl). 2011; 124(22):3786-3793.
9.Nan Jiang, Genshu Wang, Jian Zhang, Hua Li, Guo-Ying Wang, Yang Yang, Guihua Chen; Development of a chip assay for detecting CYP3A5 and MDR1 genetic polymorphism in liver transplantation patients to guide individualize immunosuppressive therapy. Hepatology, 2011, 54(4):653A.
10.Zhang YC, Zhang Q, Li H, Zhang J, Wang GS, Xu C, Yi SH, Yi HM, Cai CJ, Lu MQ, Yang Y, Chen GH. Prognostic factors for late mortality after liver transplantation for benign end-stage liver disease. Chin Med J (Engl). 2011, 124(24):4229-35.
11.Guo-Ying Wang, Jian Zhang, Hua Li, Nan Jiang, Qi Zhang. A preoperative prognostic score system based on preoperative neutrophil to lymphocyte ratio for predicting the recurrence of hepatitis B virus-associated hepatocellular carcinoma after liver transplantation. Hepatology. 2011; 54(4):626A.
12.Guo-Ying Wang, Jian Zhang, Wei Liu, Genshu Wang, Minru Li, Gui-Hua Chen. Preopertative serum alpha-fetoprotein level has no prognostic role in patients undergoing liver transplantation for HBV-associated hepatocellular carcinoma without vascular invasion. Hepatology. 2012; 56(S1):506A.
13.Na Ning, Kang CHEN, Jian ZHANG, Shanyang HE, Qiang FU, Beili ZHU, Kaiyuan CAO, Lin XU. Tumor antigen-pulsed CD8α+ dendritic cells induce T cell-mediated graft-versus-tumor effect in vitro. Journal Hua Zhong University of Science and Technology (Medical Sciences). 2011; 31(6):728-734.
14.Guo-Ying Wang, Yang Yang, Hua Li, Jian Zhang, Nan Jiang, Min-Ru Li, Huan-Bing Zhu, Qi Zhang, Gui-Hua Chen. A scoring model based on neutrophil to lymphocyte ratio predicts recurrence of HBV-associated hepatocellular carcinoma after liver transplantation. PLoS One. 2011; 6(9):e25295.
15.Guo-Ying Wang, Yang Yang, Hua Li, Jian Zhang, Min-Ru Li, Qi Zhang, Gui-Hua Chen. Rapamycin combined with donor immature dendritic cells promotes liver allograft survival in association with CD4+CD25+Foxp3+ regulatory T cells expansion. Hepatology Research. 2012; 42(2):192-202.
16.Guo-Ying Wang, Gui-Hua Chen, Hua Li, Yong Huang, Jian Zhang, Nan Jiang, Wei-Jin Chen. Rapamycin inhibits activator protein 1 but not nuclear factor κB activity of mature bone marrow derived dendritic dells. Transplantation proceedings. 2010; 42(6):1881-1883.
17.Guo-Ying Wang, Qi Zhang Hua Li, Jian Zhang, Nan Jiang. Combination of immature dendritic cells infusion with a short postoperative course of rapamycin promotes liver allograft survival in association with regulatory T cells expansion. Hepatology. 2011; 54(4):691A.
18.Guo-ying Wang, Yang Yang, Qi Zhang, Hua Li, Jian Zhang, Nan Jiang, Gui-hua Chen. Preoperative neutrophil to lymphocyte ratio as a prognostic predictor after liver transplantation for hepatocellular carcinoma. Liver Transplantation. 2011; 17(6):S87.
19.Genshu Wang, Nan Jiang, Minru Li, Qi Zhang, Jian Zhang, Hua Li. Health-related quality of life after liver transplantation and its impact factors: expierence from a Chinese single center. Hepatology, 2011, 54(4):657A.
Contact
Third Affiliated Hospital of Sun Yat-Sen University
600. TianHe Road, TianHe District
GuangZhou, GuangDong Province
China, 510630
Phone: 86-20-85252276
E-mail: zhangjian629@sina.com
