Ruiyun Xu, MD

Titles

Professor of Hepatobiliary Surgery Department

Master Supervisor of Hepatobiliary Surgery Department

Standing Committee Member of the National Portal Hypertension Group

Chairman of Minimally Invasive Professional Association for Liver Diseases in Guangdong Province

Research Interests

Surgical treatment of liver cancer

Surgical treatment of portal hypertension

Surgical treatment of hepatic, biliary, pancreatic and splenic diseases

The pathogenesis of hepatocellular carcinoma

He is the chief surgeon, MD, Master supervisor of hepatobiliary surgery department in Third Affiliated Hospital of Sun Yat-sen University. He has been engaged in clinical and basic research work of primary liver cancer for many years. He accumulated rich clinical experience in surgery treatment and radiofrequency ablation of liver cancer. Over the years, he was involved in the MSC (mesenchymal stem cell) treatment for liver fibrosis. He successfully completed the  first " autologous bone marrow stem cells transplantation in treatment of liver fibrosis via portal vein”. He completed the first "hand-assisted laparoscopic splenectomy for portal hypertension" in China.

Education and Experience

Work Experience

1995-1999:Resident, General Surgery, The Third Affiliated Hospital of Sun Yat-Sen University

1999.01-1999.12:  Visiting scholar Liver Center of Duke University Medical Center

2004.07-2004.10:  Visiting scholar University of British Columbia,

1996-now: Master Supervisor of Hepatobiliary Surgery Department, theThird Affiliated Hospital of Sun Yat-Sen University

Certifications

1978.09-1983.07: Doctor Degree, Surgery, Jiangxi Medical University

· 1987.  Master Degree, Surgery, Sun Yat-sen University

Publications

[1] Lin Nan, Hu Kupeng, Chen Si，Xie S, Tang Z, Lin Jizong, Xu Ruiyun(correspondence author). Nerve growth factor-mediated paracrine regulation of hepatic stellate cells by multipotent mesenchymal stromal cells. Life Sci, 2009, 85(7-8): 291-5.

[2]Lin N, Chen S, Pan W, Xu L, Hu K, Xu Ruiyun(correspondence author). NP603, a novel and potent inhibitor of FGFR1 tyrosine kinase, inhibits hepatic stellate cell proliferation and ameliorates hepatic fibrosis in rats. Am J Physiol Cell Physiol. 2011. 301(2): C469-77

[3]Chen S, Xu L, Lin N, Pan W, Hu K, Xu Ruiyun(correspondence author). Activation of Notch1 signaling by marrow-derived mesenchymal stem cells through cell-cell contact inhibits proliferation of hepatic stellate cells. Life Sci. 2011. 89(25-26): 975-81.

[4]Lin Nan, Tang Z, Deng M, Zhong Y, Lin Jizong,Yang X, Xiang P, Xu Ruiyun(correspondence author). Hedgehog-mediated paracrine interaction between hepatic stellate cells and marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun,2008,372(1):260-265.

[5]Zhong Yuesi, Lin Nan, Deng M, Zhang F, Tang Z, Xu Ruiyun（correspondence author）. Deficient proliferation of bone marrow-derived mesenchymal stem cells in patients with chronic hepatitis B viral infections and cirrhosis of the liver. Dig Dis Sci, 2010,55(2): 438-45.

[6]Fang H, Lin Nan, Deng M, Zhang F, Tang Z, Xu Ruiyun（correspondence author）. A Novle Canine Model of Esophageal Varices with a Ballon Dilatation Constrictor. Dig Dis Sci, 2009,54:1449-1455.

[7]Lin Nan, Lin Jizong，Liu bo，Pan weidong，chen si, Xu Ruiyun（correspondence author）Differentiation of bone marrow-derived mesenchymal stem cells into hepatocyte-like cells in an alginate scaffold . Cell proliferation 2010,43.427-434

[8]Cao BQ, Lin JZ, Zhong YS, Huang SB, Lin Nan, Tang ZF, Chen R, Xiang P, Xu Ruiyun（correspondence author）. Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats. World J Gastroenterol ,2007,13(12): 1851-4; discussion 1854-6.

Contact

Department of Hepatobiliary Surgery, Third Affiliated Hospital of Sun Yat-Sen University

NO.600 TianHe Road, Guangzhou City, 510630, Guangdong Province, China

Email: drxuruiyun@gmail.com

Fax: 86-20-85253178.

Appointment Phone: 13809775140